Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.100 None 0.992 118 0 1988 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.100 None 1.000 42 0 2000 2020
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.340 None 1.000 5 0 2008 2020
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1
P11166 solute carrier family 2 member 1 Transporter 687 0.388 0.808 0.99 0.340 None 1.000 4 0 2010 2020
Entrez Id: 768
Gene Symbol: CA9
CA9
Q16790 carbonic anhydrase 9 226 0.483 0.731 1.3E-09 0.330 None 1.000 3 0 2010 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.020 None 1.000 2 0 2006 2020
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
P00325 alcohol dehydrogenase 1B (class I), beta polypeptide Enzyme 224 0.502 0.846 9.9E-07 0.010 None 1.000 1 0 2020 2020
Entrez Id: 127
Gene Symbol: ADH4
ADH4
P08319 alcohol dehydrogenase 4 (class II), pi polypeptide Enzyme 53 0.641 0.462 8.1E-07 0.010 None 1.000 1 0 2020 2020
Entrez Id: 3021
Gene Symbol: H3-3B
H3-3B
P84243 H3.3 histone B 77 0.599 0.385 0.81 0.010 None 1.000 1 0 2020 2020
Entrez Id: 25797
Gene Symbol: QPCT
QPCT
Q16769 glutaminyl-peptide cyclotransferase Enzyme 94 0.568 0.731 1.2E-15 0.010 None 1.000 1 0 2020 2020
Entrez Id: 3020
Gene Symbol: H3-3A
H3-3A
P84243 H3.3 histone A 134 0.559 0.692 0.12 0.010 None 1.000 1 0 2020 2020
Entrez Id: 2533
Gene Symbol: FYB1
FYB1
O15117 FYN binding protein 1 30 0.711 0.538 0.24 0.010 None 1.000 1 0 2020 2020
Entrez Id: 192
Gene Symbol: AIC
AIC
Aicardi syndrome 21 0.729 0.462 0.010 None 1.000 1 0 2020 2020
Entrez Id: 1515
Gene Symbol: CTSV
CTSV
O60911 cathepsin V Enzyme 22 0.716 0.462 2.3E-07 0.010 None 1.000 1 0 2020 2020
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
P48735 isocitrate dehydrogenase (NADP(+)) 2 380 0.434 0.808 0.88 0.010 None 1.000 1 0 2020 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.975 40 0 1994 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.100 None 1.000 22 0 1995 2019
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
P02545 lamin A/C 824 0.384 0.885 1.00 0.100 None 0.952 21 0 2000 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.200 None 1.000 19 2 2003 2019
Entrez Id: 5241
Gene Symbol: PGR
PGR
P06401 progesterone receptor Nuclear receptor 392 0.426 0.885 5.1E-02 0.100 None 1.000 16 0 1998 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.090 None 0.889 9 0 2002 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.090 None 0.778 9 0 2010 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.080 None 1.000 8 0 2004 2019
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.050 None 1.000 5 0 2011 2019
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.040 None 0.750 4 0 2002 2019